We are a chemistry lab applying organic synthesis in medicinal chemistry and chemical biology. Central to our work is synthetic methods development and discovery of molecules that improve human health.
![]() Synthetic MethodsMethods that install boron and silicon atoms into carbon-carbon bonds |
![]() Mitochondrial UncouplersSmall molecule drug discovery program for the treatment of obesity, fatty liver disease, metabolic diseases, and aging |
SphK InhibitorsDevelopment of sphingosine kinase (SphK) 1 & 2 inhibitors as medicine for multiple sclerosis, metastatic cancers and kidney fibrosis |
S1P TransportersMedicinal chemistry program to inhibit sphingosine-1-phosphate transport for the treatment of chronic kidney disease and multiple sclerosis |